An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery /

An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery / editors, Steven A. Haney and Doug Bowman ; associate editors, Arijit Chakravarty, Anthony Davies, and Caroline Shamu. - 1 online resource.

Includes bibliographical references and index.

Introduction / Steven Haney -- Fluorescence and cell labeling / Anthony Davies, Steven Haney -- Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman -- Image processing / John Bradley, Doug Bowman, Arijit Chakravarty -- Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney -- Informatics considerations / Jay Copeland, Caroline Shamu -- Basic high content assay development / Steven Haney, Doug Bowman -- Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman -- Analyzing well-level data / Steven Haney, Arijit Chakravarty -- Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty -- Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu -- Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight -- High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty -- Factoring and clustering high content data / Steven Haney, Arijit Chakravarty -- Supervised machine learning / Jeff Palmer, Arijit Chakravarty.



9781118859476 1118859472 0470624566 9780470624562

2014027680


Drugs--Analysis.
Drug development.
Drug Design.
Systems Biology--methods.
Data Interpretation, Statistical.
Drug Evaluation, Preclinical--methods.
Image Processing, Computer-Assisted--methods.
Models, Biological.
MEDICAL--Pharmacology.
Drug development.
Drugs--Analysis.


Electronic books.
Electronic books.

RM301.25

615.1/9

QV 26.5