TY - BOOK AU - Anderson,Rosaleen J. ED - Wiley InterScience (Online service) TI - Antibacterial agents: chemistry, mode of action, mechanisms of resistance, and clinical applications SN - 9781118325421 AV - RM409 .A58 2012eb U1 - 615.7922 23 PY - 2012/// CY - Oxford PB - Wiley-Blackwell KW - Antibacterial agents KW - fast KW - Electronic books N1 - Includes bibliographical references and index; Introduction to microorganisms and antibacterial chemotherapy -- Agents targeting DNA -- Agents targeting metabolic processes -- Agents targeting protein synthesis -- Agents targeting cell-wall synthesis N2 - "Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated "lab-to-clinic" approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements."-- UR - http://dx.doi.org/10.1002/9781118325421 ER -