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Olsen, Bernard A., 1953-

Hydrophilic interaction chromatography : a guide for practitioners / Bernard A. Olsen, Brian W. Pack. - Hoboken, New Jersey : John Wiley & Sons, Inc., [2013] - 1 online resource. - Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications . - Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications. .

Includes bibliographical references and index.

Separation mechanisms in hydrophilic interaction chromatography -- Stationary phases for HILIC -- HILIC method development -- Pharmaceutical applications of hydrophilic interaction chromatography -- Hydrophilic interaction chromatography (HILIC) for drug discovery -- Advances in hydrophilic interaction chromatography (HILIC) for biochemical applications -- HILIC-MS for targeted metabolomics and small molecule bioanalysis -- HILIC for food, environmental, and other applications -- Theory and practice of two-dimensional liquid chromatography separations involving the HILIC mode of separation.

"This book provides background information, guidance for method development, and a discussion of applications in the field of hydrophilic interaction chromatography (HILIC.) The book serves as a valuable reference tool for scientists confronted with an analysis problem involving polar compounds to determine if HILIC would be a good choice to pursue and helps them in choosing initial experimental conditions. The book gives a detailed description of the HILIC retention mechanisms and specific information regarding application areas spanning a wide range of industries. Topics include: HILIC retention mechanisms, Stationary Phases for HILIC, HILIC Method Development, Pharmaceutical and Other Applications of HILIC, HILIC for Drug Discovery, HILIC in Two-Dimensional Separations"-- "Covers in detail HILIC retention mechanism, including background on the HILIC mode, what differences it from other HPLC modes, and retention mechanisms that can come into play"--



ISBN: 9781118495216 1118495217 9781118495230 1118495233 9781118495247 1118495241

Publisher. No.: EB00063751 Recorded Books

Subjects--Topical Terms:
Hydrophilic interaction liquid chromatography.
Chirality.
Chromatography, Liquid.
Hydrophilic interaction liquid chromatography.
Liquid chromatography.
SCIENCE--Chemistry--Analytic.
Hydrophilic interaction liquid chromatography.

Index Terms--Genre/Form:
Electronic books.

LC Class. No.: QD79.C454 / O47 2013eb

Dewey Class. No.: 543/.84