Models and Algorithms for Biomolecules and Molecular Networks. (Record no. 18762)

MARC details
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fixed length control field 06411cam a2200553Ma 4500
001 - CONTROL NUMBER
control field ocn934770313
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20230823095525.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160115s2016 xx a ob 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency IDEBK
Language of cataloging eng
Description conventions pn
Transcribing agency IDEBK
Modifying agency EBLCP
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-- OHI
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-- OCLCQ
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019 ## -
-- 934678502
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1119162262
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781119162261
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781119162254
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1119162254
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 0470601930
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 1119162270
029 1# - (OCLC)
OCLC library identifier AU@
System control number 000058381123
029 1# - (OCLC)
OCLC library identifier GBVCP
System control number 866469192
029 1# - (OCLC)
OCLC library identifier DEBSZ
System control number 480346364
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)934770313
Canceled/invalid control number (OCoLC)934678502
037 ## - SOURCE OF ACQUISITION
Stock number 887435
Source of stock number/acquisition MIL
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QP801.B69
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572
Edition number 23
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name DasGupta, Bhaskar.
245 10 - TITLE STATEMENT
Title Models and Algorithms for Biomolecules and Molecular Networks.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc UNITED STATES :
Name of publisher, distributor, etc Wiley-IEEE Press,
Date of publication, distribution, etc 2016.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (263 pages) :
Other physical details illustrations.
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-- online resource
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490 0# - SERIES STATEMENT
Series statement IEEE Press Series on Biomedical Engineering ;
Volume number/sequential designation 30
588 0# -
-- Print version record.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note List of Figures xiii -- List of Tables xix -- Foreword xxi -- Acknowledgments xxiii -- 1 Geometric Models of Protein Structure and Function Prediction 1 -- 1.1 Introduction, 1 -- 1.2 Theory and Model, 2 -- 1.2.1 Idealized Ball Model, 2 -- 1.2.2 Surface Models of Proteins, 3 -- 1.2.3 Geometric Constructs, 4 -- 1.2.4 Topological Structures, 6 -- 1.2.5 Metric Measurements, 9 -- 1.3 Algorithm and Computation, 13 -- 1.4 Applications, 15 -- 1.4.1 Protein Packing, 15 -- 1.4.2 Predicting Protein Functions from Structures, 17 -- 1.5 Discussion and Summary, 20 -- References, 22 -- Exercises, 25 -- 2 Scoring Functions for Predicting Structure and Binding of Proteins 29 -- 2.1 Introduction, 29 -- 2.2 General Framework of Scoring Function and Potential Function, 31 -- 2.2.1 Protein Representation and Descriptors, 31 -- 2.2.2 Functional Form, 32 -- 2.2.3 Deriving Parameters of Potential Functions, 32 -- 2.3 Statistical Method, 32 -- 2.3.1 Background, 32 -- 2.3.2 Theoretical Model, 33 -- 2.3.3 Miyazawa -- Jernigan Contact Potential, 34 -- 2.3.4 Distance-Dependent Potential Function, 41 -- 2.3.5 Geometric Potential Functions, 45 -- 2.4 Optimization Method, 49 -- 2.4.1 Geometric Nature of Discrimination, 50 -- 2.4.2 Optimal Linear Potential Function, 52 -- 2.4.3 Optimal Nonlinear Potential Function, 53 -- 2.4.4 Deriving Optimal Nonlinear Scoring Function, 55 -- 2.4.5 Optimization Techniques, 55 -- 2.5 Applications, 55 -- 2.5.1 Protein Structure Prediction, 56 -- 2.5.2 Protein -- Protein Docking Prediction, 56 -- 2.5.3 Protein Design, 58 -- 2.5.4 Protein Stability and Binding Affinity, 59 -- 2.6 Discussion and Summary, 60 -- 2.6.1 Knowledge-Based Statistical Potential Functions, 60 -- 2.6.2 Relationship of Knowledge-Based Energy Functions and Further Development, 64 -- 2.6.3 Optimized Potential Function, 65 -- 2.6.4 Data Dependency of Knowledge-Based Potentials, 66 -- References, 67 -- Exercises, 75 -- 3 Sampling Techniques: Estimating Evolutionary Rates and Generating Molecular Structures 79.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 3.1 Introduction, 79 -- 3.2 Principles of Monte Carlo Sampling, 81 -- 3.2.1 Estimation Through Sampling from Target Distribution, 81 -- 3.2.2 Rejection Sampling, 82 -- 3.3 Markov Chains and Metropolis Monte Carlo Sampling, 83 -- 3.3.1 Properties of Markov Chains, 83 -- 3.3.2 Markov Chain Monte Carlo Sampling, 85 -- 3.4 Sequential Monte Carlo Sampling, 87 -- 3.4.1 Importance Sampling, 87 -- 3.4.2 Sequential Importance Sampling, 87 -- 3.4.3 Resampling, 91 -- 3.5 Applications, 92 -- 3.5.1 Markov Chain Monte Carlo for Evolutionary Rate Estimation, 92 -- 3.5.2 Sequentail Chain Growth Monte Carlo for Estimating Conformational Entropy of RNA Loops, 95 -- 3.6 Discussion and Summary, 96 -- References, 97 -- Exercises, 99 -- 4 Stochastic Molecular Networks 103 -- 4.1 Introduction, 103 -- 4.2 Reaction System and Discrete Chemical Master Equation, 104 -- 4.3 Direct Solution of Chemical Master Equation, 106 -- 4.3.1 State Enumeration with Finite Buffer, 106 -- 4.3.2 Generalization and Multi-Buffer dCME Method, 108 -- 4.3.3 Calculation of Steady-State Probability Landscape, 108 -- 4.3.4 Calculation of Dynamically Evolving Probability Landscape, 108 -- 4.3.5 Methods for State Space Truncation for Simplification, 109 -- 4.4 Quantifying and Controlling Errors from State Space Truncation, 111 -- 4.5 Approximating Discrete Chemical Master Equation, 114 -- 4.5.1 Continuous Chemical Master Equation, 114 -- 4.5.2 Stochastic Differential Equation: Fokker -- Planck Approach, 114 -- 4.5.3 Stochastic Differential Equation: Langevin Approach, 116 -- 4.5.4 Other Approximations, 117 -- 4.6 Stochastic Simulation, 118 -- 4.6.1 Reaction Probability, 118 -- 4.6.2 Reaction Trajectory, 118 -- 4.6.3 Probability of Reaction Trajectory, 119 -- 4.6.4 Stochastic Simulation Algorithm, 119 -- 4.7 Applications, 121 -- 4.7.1 Probability Landscape of a Stochastic Toggle Switch, 121 -- 4.7.2 Epigenetic Decision Network of Cellular Fate in Phage Lambda, 123 -- 4.8 Discussions and Summary, 127 -- References, 128.
520 ## - SUMMARY, ETC.
Summary, etc By providing expositions to modeling principles, theories, computational solutions, and open problems, this reference presents a full scope on relevant biological phenomena, modeling frameworks, technical challenges, and algorithms. -Up-to-date developments of structures of biomolecules, systems biology, advanced models, and algorithms -Sampling techniques for estimating evolutionary rates and generating molecular structures -Accurate computation of probability landscape of stochastic networks, solving discrete chemical master equations -End-of-chapter exercises.
526 ## - STUDY PROGRAM INFORMATION NOTE
Department Life Sciences
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomolecules.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Structure-activity relationships (Biochemistry)
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomolecules.
Source of heading or term fast
-- (OCoLC)fst00832624
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Structure-activity relationships (Biochemistry)
Source of heading or term fast
-- (OCoLC)fst01135737
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element SCIENCE / Life Sciences / Biophysics.
Source of heading or term bisacsh
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1002/9781119162254">http://dx.doi.org/10.1002/9781119162254</a>
Public note Wiley Online Library
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