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Analytical methods for therapeutic drug monitoring and toxicology / Q. Alan Xu and Timothy L. Madden.

By: Contributor(s): Material type: TextTextPublication details: Hoboken, N.J. : Wiley, ©2011.Description: 1 online resource (xiv, 502 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780470909782
  • 0470909781
  • 9780470909799
  • 047090979X
Subject(s): Genre/Form: Additional physical formats: Print version:: Analytical methods for therapeutic drug monitoring and toxicology.DDC classification:
  • 615/.19 22
LOC classification:
  • RS189 .X8 2010eb
NLM classification:
  • WB 330
Online resources:
Contents:
US adopted name -- Drug category -- Chemical name -- Other names -- Molecular formula -- Molecular weight -- CAS number -- Appearance -- Solubilities -- pKa value(s) -- Individual(s) who developed or published the method -- Drug that was analyzed -- Description of analytical system components -- Description of major operating parameters -- Standard solution preparation -- Sample preparation (dilution, liquid-liquid or SPE extraction, derivatization, etc.) -- Dynamic concentration range of the calibration curve -- Correlation coefficient and linearity -- Coefficient of variation of the assay -- Intraday and interday coefficients of variation of samples -- Limit of detection and limit of quantification -- Interference.
Summary: This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatogr.
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Includes bibliographical references and index.

US adopted name -- Drug category -- Chemical name -- Other names -- Molecular formula -- Molecular weight -- CAS number -- Appearance -- Solubilities -- pKa value(s) -- Individual(s) who developed or published the method -- Drug that was analyzed -- Description of analytical system components -- Description of major operating parameters -- Standard solution preparation -- Sample preparation (dilution, liquid-liquid or SPE extraction, derivatization, etc.) -- Dynamic concentration range of the calibration curve -- Correlation coefficient and linearity -- Coefficient of variation of the assay -- Intraday and interday coefficients of variation of samples -- Limit of detection and limit of quantification -- Interference.

Print version record.

This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatogr.

Pharmacy