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Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds / Florencioa Zaragoza Dörwald.

By: Material type: TextTextPublisher: Weinheim : Wiley-VCH Verlag GmBH & Co., [2012]Copyright date: ©2012Description: 1 online resource (xvi, 605 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9783527645640
  • 3527645640
  • 9783527645664
  • 3527645667
Subject(s): Genre/Form: Additional physical formats: Print version:: Lead optimization for medicinal chemists.DDC classification:
  • 615.19
LOC classification:
  • RS403
Online resources:
Contents:
pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.
Summary: Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.
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Online resource; title from home page (viewed May 23, 2014).

Includes bibliographical references and index.

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.

pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.

Pharmacy