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A comprehensive and up-to-date overview of alkyne chemistry, taking into account the progress made over the last two decades. The experienced editors are renowned world leaders in the field, while the list of contributors reads like a "Who's Who" of synthetic organic chemistry. The result is a valuable reference not only for organic chemists at universities and in the chemical industry, but also for biologists and material scientists involved in the modern synthesis of organic compounds and materials.

Front Matter -- Introduction / Chao-Jun Li, Barry M Trost -- Part I: Catalytic Isomerization of Alkynes. Redox Isomerization of Propargyl Alcohols to Enones / Barry M Trost -- Carbophilic Cycloisomerization Reactions of Enynesand Domino Processes / Jean-Pierre Genet, Patrick Y Toullec, Véronique Michelet -- Alkyne Metathesis in Organic Synthesis / Alois Fürstner -- Part II: Catalytic Cycloaddition Reactions. Alkyne-Azide Reactions / Sanne Schoffelen, Morten Meldal -- Catalytic Cycloaddition Reactions / Fiona R Truscott, Giovanni Maestri, Raphael Rodriguez, Max Malacria -- Part III: Catalytic Nucleophilic Additions and Substitutions. Catalytic Conjugate Additions of Alkynes / Naoya Kumagai, Masakatsu Shibasaki -- Catalytic Enantioselective Addition of Terminal Alkynes to Carbonyls / Barry M Trost, Mark J Bartlett -- Catalytic Nucleophilic Addition of Alkynes to Imines: The A (Aldehyde-Alkyne-Amine) Coupling / Nick Uhlig, Woo-Jin Yoo, Liang Zhao, Chao-Jun Li -- The Sonogashira Reaction / Rafael Chinchilla, Carmen Nájera -- Part IV: Other Reactions. Catalytic Dimerization of Alkynes / Sergio E García-Garrido -- The Oxidative Dimerization of Acetylenes and Related Reactions: Synthesis and Applications of Conjugated 1,3-Diynes / Jean-Philip Lumb -- The Alkyne Zipper Reaction in Asymmetric Synthesis / Kenneth Avocetien, Yu Li, George A O'Doherty -- Index.