TY  - BOOK
AU  - Dörwald,Florencio Zaragoza
TI  - Lead optimization for medicinal chemists: pharmacokinetic properties of functional groups and organic compounds 
SN  - 9783527645640
AV  - RS403 
U1  - 615.19 
PY  - 2012///]
CY  - Weinheim
PB  - Wiley-VCH Verlag GmBH & Co.
KW  - Pharmaceutical chemistry
KW  - MEDICAL
KW  - Drug Guides
KW  - bisacsh
KW  - Nursing
KW  - Pharmacology
KW  - Pharmacy
KW  - fast
KW  - Electronic books
KW  - local
N1  - Includes bibliographical references and index; pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes; phr
N2  - Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy
UR  - http://dx.doi.org/10.1002/9783527645640
ER  -