TY - BOOK AU - Bertini,Ivano AU - McGreevy,Kathleen S. AU - Parigi,Giacomo ED - Wiley InterScience (Online service) TI - NMR of biomolecules: towards mechanistic systems biology SN - 9783527644506 AV - QP519.9.N83 N67 2012 U1 - 572 23 PY - 2012///] CY - Weinheim, Germany PB - Wiley-VCH KW - Biomolecules KW - Biological systems KW - Nuclear magnetic resonance spectroscopy KW - Systems biology KW - Nuclear Magnetic Resonance, Biomolecular KW - Proteins KW - chemistry KW - Nucleic Acids KW - Systems Biology KW - SCIENCE KW - Life Sciences KW - Biochemistry KW - bisacsh KW - fast KW - Biomolekül KW - gnd KW - NMR-Spektroskopie KW - Electronic books N1 - Includes bibliographical references and index; Introduction. NMR and its Place in Mechanistic Systems Biology; Ivano Bertini, Kathleen S McGreevy, Giacomo Parigi --; Structure of Biomolecules: Fundamentals; Lucia Banci, Francesca Cantini, Mirko Cevec, Hendrik R A Jonker, Senada Nozinovic, Christian Richter, Harald Schwalbe --; What Can be Learned about the Structure and Dynamics of Biomolecules from NMR; Lucio Ferella, Antonio Rosato, Paola Turano, Janez Plavec --; Role of NMR in the Study of the Structure and Dynamics of Biomolecules. Determination of Protein Structure and Dynamics; Lucio Ferella, Antonio Rosato, Paola Turano --; DNA; Janez Plavec --; RNA; Richard ⁽tefl, Vladim̕r Skleǹr --; Intrinsically Disordered Proteins; Isabella C Felli, Roberta Pierattelli, Peter Tompa --; Paramagnetic Molecules; Ivano Bertini, Claudio Luchinat, Giacomo Parigi --; Role of NMR in the Study of the Structure and Dynamics of Biomolecular Interactions. NMR Methodologies for the Analysis of Protein₆Protein Interactions; Tobias Madl, Michael Sattler -- Metal-Mediated Interactions; Simone Ciofi-Baffoni --; Protein₆Paramagnetic Protein Interactions; Peter H J Keizers, Yoshitaka Hiruma, Marcellus Ubbink --; Protein₆RNA Interactions; Vijayalaxmi Manoharan, Jose Manuel P̌rez-Cąadillas, Andres Ramos --; Protein₆DNA Interactions; Lidija Kovacic, Rolf Boelens --; NMR in Drug Discovery. High-Throughput Screening and Fragment-Based Design: General Considerations for Lead Discovery and Optimization; Maurizio Pellecchia --; Ligand-Observed NMR in Fragment-Based Approaches; Pawel Sledz, Chris Abell, Alessio Ciulli --; Interactions of Metallodrugs with DNA; Hong-Ke Liu, Peter J Sadler --; RNA as a Drug Target; Jan-Peter Ferner, Elke Duchardt Ferner, J̲rg Rinnenthal, Janina Buck, Jens W̲hnert, Harald Schwalbe --; Fluorine NMR Spectroscopy for Biochemical Screening in Drug Discovery; Claudio Dalvit --; NMR of Peptides; Johannes G Beck, Andreas O Frank, Horst Kessler --; Solid-State NMR. Biomolecular Solid-State NMR/Basics; Emeline Barbet-Massin, Guido Pintacuda --; Protein Dynamics in the Solid State; J̤zef R Lewandowski, Lyndon Emsley --; Microcrystalline Proteins ₆ An Ideal Benchmark for Methodology Development; W Trent Franks, Barth-Jan van Rossum, Benjamin Bardiaux, Enrico Ravera, Giacomo Parigi, Claudio Luchinat, Hartmut Oschkinat --; Structural Studies of Protein Fibrils by Solid-State NMR; Anja B̲ckmann, Beat H Meier --; Solid-State NMR on Membrane Proteins: Methods and Applications; A A Cukkemane, M Renault, M Baldus --; Frontiers in NMR Spectroscopy. Dynamic Nuclear Polarization; Thomas F Prisner --; C Direct Detection NMR; Isabella C Felli, Roberta Pierattelli --; Speeding up Multidimensional NMR Data Acquisition; Bernhard Brutscher, Dominique Marion, Lucio Frydman --; Metabolomics; Leonardo Tenori --; In-Cell Protein NMR Spectroscopy; David S Burz, David Cowburn, Kaushik Dutta, Alexander Shekhtman --; Structural Investigation of Cell-Free Expressed Membrane Proteins; Solmaz Sobhanifar, Sina Reckel, Frank L̲hr, Frank Bernhard, Volker D̲tsch --; Computational Aspects. Grid Computing; Antonio Rosato --; Protein₆Protein Docking with HADDOCK; Christophe Schmitz, Adrien S J Melquiond, Sjoerd J de Vries, Ezgi Karaca, Marc van Dijk, Panagiotis L Kastritis, Alexandre M J J Bonvin --; Automated Protein Structure Determination Methods; Paul Guerry, Torsten Herrmann --; NMR Structure Determination of Protein₆Ligand Complexes; Ulrich Schieborr, Sridhar Sreeramulu, Harald Schwalbe --; Small Angle X-Ray Scattering/Small Angle Neutron Scattering as Methods Complementary to NMR; M V Petoukhov, D I Svergun; ls UR - http://dx.doi.org/10.1002/9783527644506 ER -