TY - BOOK AU - Olsen,Bernard A. AU - Pack,Brian W. TI - Hydrophilic interaction chromatography: a guide for practitioners T2 - Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications SN - 9781118495216 AV - QD79.C454 O47 2013eb U1 - 543/.84 23 PY - 2013///] CY - Hoboken, New Jersey PB - John Wiley & Sons, Inc. KW - Hydrophilic interaction liquid chromatography KW - Chirality KW - Chromatography, Liquid KW - Liquid chromatography KW - SCIENCE KW - Chemistry KW - Analytic KW - bisacsh KW - fast KW - Electronic books N1 - Includes bibliographical references and index; Separation mechanisms in hydrophilic interaction chromatography -- Stationary phases for HILIC -- HILIC method development -- Pharmaceutical applications of hydrophilic interaction chromatography -- Hydrophilic interaction chromatography (HILIC) for drug discovery -- Advances in hydrophilic interaction chromatography (HILIC) for biochemical applications -- HILIC-MS for targeted metabolomics and small molecule bioanalysis -- HILIC for food, environmental, and other applications -- Theory and practice of two-dimensional liquid chromatography separations involving the HILIC mode of separation; env N2 - "This book provides background information, guidance for method development, and a discussion of applications in the field of hydrophilic interaction chromatography (HILIC.) The book serves as a valuable reference tool for scientists confronted with an analysis problem involving polar compounds to determine if HILIC would be a good choice to pursue and helps them in choosing initial experimental conditions. The book gives a detailed description of the HILIC retention mechanisms and specific information regarding application areas spanning a wide range of industries. Topics include: HILIC retention mechanisms, Stationary Phases for HILIC, HILIC Method Development, Pharmaceutical and Other Applications of HILIC, HILIC for Drug Discovery, HILIC in Two-Dimensional Separations"--; "Covers in detail HILIC retention mechanism, including background on the HILIC mode, what differences it from other HPLC modes, and retention mechanisms that can come into play"-- UR - http://dx.doi.org/10.1002/9781118495247 ER -