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001 ocn805654697
003 OCoLC
005 20221117120748.0
006 m o d
007 cr |||||||||||
008 120809t20122012gw a ob 001 0 eng d
040 _aYDXCP
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019 _a961515877
_a962633579
_a966211547
020 _a9783527645640
020 _a3527645640
020 _a9783527645664
020 _a3527645667
020 _z9783527332267
020 _z352733226X
020 _z9783527645657
020 _z3527645659
020 _z9783527645671
020 _z3527645675
020 _z9781283893244
020 _z128389324X
029 1 _aAU@
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029 1 _aAU@
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029 1 _aNZ1
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029 1 _aGBVCP
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035 _a(OCoLC)805654697
_z(OCoLC)961515877
_z(OCoLC)962633579
_z(OCoLC)966211547
050 4 _aRS403
072 7 _aMED
_x023000
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082 0 4 _a615.19
049 _aMAIN
100 1 _aDörwald, Florencio Zaragoza.
245 1 0 _aLead optimization for medicinal chemists :
_bpharmacokinetic properties of functional groups and organic compounds /
_cFlorencioa Zaragoza Dörwald.
264 1 _aWeinheim :
_bWiley-VCH Verlag GmBH & Co.,
_c[2012]
264 4 _c©2012
300 _a1 online resource (xvi, 605 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
380 _aBibliography
588 0 _aOnline resource; title from home page (viewed May 23, 2014).
504 _aIncludes bibliographical references and index.
520 _aSmall structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.
505 0 _apt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.
650 0 _aPharmaceutical chemistry.
650 7 _aMEDICAL
_xDrug Guides.
_2bisacsh
650 7 _aMEDICAL
_xNursing
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
650 7 _aPharmaceutical chemistry.
_2fast
_0(OCoLC)fst01060115
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
776 0 8 _iPrint version:
_aDörwald, Florencio Zaragoza.
_tLead optimization for medicinal chemists.
_dWeinheim : Wiley-VCH, ©2012
_z9783527332267
_w(OCoLC)793414338
856 4 0 _uhttp://dx.doi.org/10.1002/9783527645640
_zWiley Online Library
994 _a92
_bDG1
999 _c19703
_d19662
526 _bphr